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Growth Hormone and Epidermal Growth Factor in Salivary Glands of Giant and Dwarf Transgenic MicePublished by: Journal of Histochemistry & Cytochemistry Epidermal growth factor (EGF) in rat salivary glands is regulated by testosterone, thyroxin, and growth hormone (GH). Salivary glands of 45-day-old giant and dwarf male and female transgenic mice were examined histologically and by immunohistochemistry (IHC) for EGF. Male giants showed no significant differences from wild-type (WT) parotid and submandibular glands. Authors: William G. Young, German O. Ramirez-Yañez, Terry J. Daley, Joseph R. Smid, Karen T. Coshigano, John J. Kopchick, and Michael J. Waters germàn o ramirez-yañez, growth hormone, dwarf transgenic mice, william g young, salivary glands, epidermal growth factor |
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Influence of Growth Hormone on the Mandibular Condylar Cartilage of RatsPublished by: Archives of Oral Biology (2004) Growth hormone (GH) stimulates mandibular growth but its effect on the mandibular condylar cartilage is not well understood. This study was designed to understand the influence of GH on mitotic activity and on chondrocytes maturation. The effect of GH on cartilage thickness was also determined. Authors: Germàn O. Ramirez-Yañez, William G. Younga, Terry J. Daleya and Michael J. Waters germàn o ramirez-yañez, mandibular condylar cartilage, growth hormone, human craniofacial growth |
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Influence of growth hormone on the craniofacial complex of transgenic micePublished by: The European Journal of Orthodontics Growth hormone (GH) secretion affects bone and cartilage physiology. This study investigated the effect of GH on the size of the craniofacial structures and their angular relationship. Three different models of mice with a genetically altered GH axis were used: GH excess (giant), dwarf GH antagonist (dwarf-Ant), and dwarf GH receptor knockout (dwarf-KO) mice. Authors: German Omar Ramirez-Yañez, Joseph R. Smid, William George Young and Michael J. Waters growth hormone, transgenic mice, bone and cartilage physiology, craniofacial complex |
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