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Influence of growth hormone on the craniofacial complex of transgenic mice

Published by: The European Journal of Orthodontics

Growth hormone (GH) secretion affects bone and cartilage physiology. This study investigated the effect of GH on the size of the craniofacial structures and their angular relationship. Three different models of mice with a genetically altered GH axis were used: GH excess (giant), dwarf GH antagonist (dwarf-Ant), and dwarf GH receptor knockout (dwarf-KO) mice.

Authors: German Omar Ramirez-Yañez, Joseph R. Smid, William George Young and Michael J. Waters

growth hormone, transgenic mice, bone and cartilage physiology, craniofacial complex