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Growth Hormone and Epidermal Growth Factor in Salivary Glands of Giant and Dwarf Transgenic Mice Published by: Journal of Histochemistry & Cytochemistry Epidermal growth factor (EGF) in rat salivary glands is regulated by testosterone, thyroxin, and growth hormone (GH). Salivary glands of 45-day-old giant and dwarf male and female transgenic mice were examined histologically and by immunohistochemistry (IHC) for EGF. Male giants showed no significant differences from wild-type (WT) parotid and submandibular glands. Authors: William G. Young, German O. Ramirez-Yañez, Terry J. Daley, Joseph R. Smid, Karen T. Coshigano, John J. Kopchick, and Michael J. Waters germàn o ramirez-yañez, growth hormone, dwarf transgenic mice, william g young, salivary glands, epidermal growth factor
The Mandibular Condylar Cartilage: a Review Published by: International Journal of Jaw Functional Orthopedics (2004) The condylar cartilage is the most important growing site in the mandible. This does not deny that other areas play an important role in mandibular growth, and influence the amount and direction of that growth. However, the condylar cartilage is responsible for the final length of the mandible. The purpose of this paper is to review the actual knowledge about the physiology of the mandibular condylar cartilage and how this cartilage responds to extrinsic and intrinsic stimulus. Author: Dr. German O. Ramirez-Yañez germàn o ramirez-yañez, mandibular growth, intrinsic stimulus, condylar cartilage
Influence of Growth Hormone on the Mandibular Condylar Cartilage of Rats Published by: Archives of Oral Biology (2004) Growth hormone (GH) stimulates mandibular growth but its effect on the mandibular condylar cartilage is not well understood. This study was designed to understand the influence of GH on mitotic activity and on chondrocytes maturation. The effect of GH on cartilage thickness was also determined. Authors: Germàn O. Ramirez-Yañez, William G. Younga, Terry J. Daleya and Michael J. Waters germàn o ramirez-yañez, mandibular condylar cartilage, growth hormone, human craniofacial growth
Incisor disocclusion in rats affects mandibular condylar cartilage at the cellular level Published by: Archives of Oral Biology The effect of altered occlusion on the mandibular condylar cartilage remains unclear. This study investigated the effect of unilateral incisor disocclusion on cartilage thickness, on mitotic activity and on chondrocytes maturation and differentiation in the mandibular condylar cartilage of rats. Author: G.O. Ramirez-Yañez, T.J. Daley, A.L. Symons and W.G. Young germàn o ramirez-yañez, mandibular condylar cartilage, cellular level, Incisor disocclusion
Soft Tissue Dysfunction: a Missing Clue when Treating Malocclusions Published by: International Journal of Jaw Functional Orthopedics (2005) Contemporaneous treatment of malocclusions concerns about the effect of the muscular activity in the occlusion. Treatment of malocclusion involves dental alignment, jaw repositioning, stabilization of the activity of the masticatory muscles, the muscles of the tongue and the muscles of the cheeks and lips in order to achieve a balance between the forces delivered on the arches and teeth by all the muscles involved in oral functions. Authors: Dr German O. Ramirez-Yañez & Dr Chris Farrell malocclusion, germàn o ramirez-yañez, soft tissue dysfunction, dental alignmen, muscular activity
Combining Functional and Fixed Appliances to Improve Results in Open Bite Treatment Published by: The American Association for Functional Orthodontics Open bite is one of the most challenging malocclusions and its treatment must aim to improve occlusion and muscular function in the masticatory system, producing a satisfactory and stable result. This clinical report presents a patient with an open bite in mixed dentition associated with a Class II, division 1 malocclusion and a posterior unilateral crossbite. By combining functional and fixed appliances, the open bite was closed, a good occlusion was reinstated and muscular activity was improved in a simpler way. Author: Dr. German O.Ramirez-Yañez germàn o ramirez-yañez, open bite treatment, fixed appliances, combining functional